We propose Hand-Object\emph{(HO)GraspFlow}, an affordance-centric approach that retargets a single RGB with hand-object interaction (HOI) into multi-modal executable parallel jaw grasps without explicit geometric priors on target objects. Building on foundation models for hand reconstruction and vision, we synthesize $SE(3)$ grasp poses with denoising flow matching (FM), conditioned on the following three complementary cues: RGB foundation features as visual semantics, HOI contact reconstruction, and taxonomy-aware prior on grasp types. Our approach demonstrates high fidelity in grasp synthesis without explicit HOI contact input or object geometry, while maintaining strong contact and taxonomy recognition. Another controlled comparison shows that \emph{HOGraspFlow} consistently outperforms diffusion-based variants (\emph{HOGraspDiff}), achieving high distributional fidelity and more stable optimization in $SE(3)$. We demonstrate a reliable, object-agnostic grasp synthesis from human demonstrations in real-world experiments, where an average success rate of over $83\%$ is achieved. Code: https://github.com/YitianShi/HOGraspFlow
